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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cul3tm1Suc
targeted mutation 1, Shinichi Uchida
MGI:5901731
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cul3tm1Suc/Cul3tm1Suc involves: C57BL/6 MGI:5901733
ht2
 		Cul3tm1Suc/Cul3+ involves: C57BL/6 MGI:5901734


Genotype
MGI:5901733
hm1
Allelic
Composition		 Cul3tm1Suc/Cul3tm1Suc
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cul3tm1Suc mutation (0 available); any Cul3 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality, complete penetrance ( J:226618 )
• no viable mice are obtained, time of lethality not specified




Genotype
MGI:5901734
ht2
Allelic
Composition		 Cul3tm1Suc/Cul3+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cul3tm1Suc mutation (0 available); any Cul3 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased circulating chloride level ( J:226618 )
• blood chloride level is slightly higher

cardiovascular system
cardiovascular system phenotype ( J:226618 )
N
• mice exhibit normal blood pressure

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT pseudohypoaldosteronism DOID:4479 J:226618




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory