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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Polntm1.2Rwd
targeted mutation 1.2, Richard D Wood
MGI:5903477
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Polntm1.2Rwd/Polntm1.2Rwd involves: 129 * C57BL/6 MGI:5903624
hm2
Polntm1.2Rwd/Polntm1.2Rwd involves: 129 * C57BL/6J * DBA/2J MGI:5903625
cx3
Polntm1.2Rwd/Polntm1.2Rwd
Polqtm1Jcs/Polqtm1Jcs
involves: 129S4/SvJae * C57BL/6J MGI:5903626


Genotype
MGI:5903624
hm1
Allelic
Composition
Polntm1.2Rwd/Polntm1.2Rwd
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polntm1.2Rwd mutation (1 available); any Poln mutation (48 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• normal litter sizes and with normal sized pups at birth with normal size, body weight, organ development, skeletal appearance, hematology or serum chemistry, tumor prevalence, multiplicity or distribution of tumor types, response of spermatid to irradiation induced DNA damage, and crossing over in B cells




Genotype
MGI:5903625
hm2
Allelic
Composition
Polntm1.2Rwd/Polntm1.2Rwd
Genetic
Background
involves: 129 * C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polntm1.2Rwd mutation (1 available); any Poln mutation (48 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• reduced meiotic double-strand breaks at a meiotic recombination hot spot harboring insertion/deletion polymorphisms compared with controls

cellular
• reduced meiotic double-strand breaks at a meiotic recombination hot spot harboring insertion/deletion polymorphisms compared with controls




Genotype
MGI:5903626
cx3
Allelic
Composition
Polntm1.2Rwd/Polntm1.2Rwd
Polqtm1Jcs/Polqtm1Jcs
Genetic
Background
involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polntm1.2Rwd mutation (1 available); any Poln mutation (48 available)
Polqtm1Jcs mutation (1 available); any Polq mutation (127 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• in spermatids as in Polqtm1Jcs homozygotes





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory