About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mettl6em1Nju
endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
MGI:5903741
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mettl6em1Nju/Mettl6em1Nju Not Specified MGI:5903744


Genotype
MGI:5903744
hm1
Allelic
Composition		 Mettl6em1Nju/Mettl6em1Nju
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettl6em1Nju mutation (0 available); any Mettl6 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:241777 )
N
• normal Mendel ratio without observable developmental defects

cellular
abnormal cell physiology ( J:241777 )
• brain and liver tissue exhibit reduced 3-methylcytidine (m3C) methyltransferases modification of tRNA compared with in wild-type mice
• however, mRNA m3C is normal in the liver




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory