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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mettl8em1Nju
endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
MGI:5903742
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mettl8em1Nju/Mettl8em1Nju Not Specified MGI:5903745


Genotype
MGI:5903745
hm1
Allelic
Composition
Mettl8em1Nju/Mettl8em1Nju
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettl8em1Nju mutation (0 available); any Mettl8 mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• normal Mendel ratio without observable developmental defects

cellular
• liver tissue exhibits reduced 3-methylcytidine (m3C) methyltransferases modification of mRNA compared with in wild-type mice
• however, tRNA m3C is normal





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory