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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ttc9tm1Vcl
targeted mutation 1, Valerie Lin
MGI:5904133
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ttc9tm1Vcl/Ttc9tm1Vcl involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:5909415
ht2
Ttc9tm1Vcl/Ttc9+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:5909416


Genotype
MGI:5909415
hm1
Allelic
Composition
Ttc9tm1Vcl/Ttc9tm1Vcl
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ttc9tm1Vcl mutation (1 available); any Ttc9 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• at age 6 weeks
• increment in mass from age 3 weeks to 6 weeks 58.5% versus 29.62% wild-type
• more ductal side branching and terminal end buds at age 6 weeks

growth/size/body
• at age P2 (J:241703)
• 5-10% higher at all ages, significant at 6 and 10 weeks of age (J:241703)
• at age 6 weeks, significant at age 3 weeks

hematopoietic system
• at age 6 weeks
• increment in mass from age 3 weeks to 6 weeks 58.5% versus 29.62% wild-type
• at age 6 weeks, significant at age 3 weeks

immune system
• at age 6 weeks
• increment in mass from age 3 weeks to 6 weeks 58.5% versus 29.62% wild-type
• at age 6 weeks, significant at age 3 weeks

integument
• more ductal side branching and terminal end buds at age 6 weeks




Genotype
MGI:5909416
ht2
Allelic
Composition
Ttc9tm1Vcl/Ttc9+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ttc9tm1Vcl mutation (1 available); any Ttc9 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• increment in mass from age 3 weeks to 6 weeks 49.7% versus 29.62% wild-type

hematopoietic system
• increment in mass from age 3 weeks to 6 weeks 49.7% versus 29.62% wild-type

immune system
• increment in mass from age 3 weeks to 6 weeks 49.7% versus 29.62% wild-type





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory