Phenotypes associated with this allele

• Allele Symbol: Tg(Myh6-Rab1a)lowGwd
• Allele Name: transgene insertion low, Gerald W Dorn II
• Allele ID: MGI:5904948
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Myh6-Rab1a)lowGwd/0	involves: FVB/N	MGI:5904951

Genotype
MGI:5904951

tg1

• Allelic Composition: Tg(Myh6-Rab1a)lowGwd/0
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased heart weight ( J:134581 )

• heart weight to body weight ratio is increased in 1 year old mice

dilated cardiomyopathy ( J:134581 )

• dilated cardiomyopathy develops in mice over 1 year of age

decreased heart left ventricle muscle contractility ( J:134581 )

• left ventricular fractional shortening is reduced in 1 year old mice

abnormal heart echocardiography feature ( J:134581 )

• end-systolic dimension and end-diastolic dimension, measured by echocardiography, are increased in 1 year old mice

muscle

dilated cardiomyopathy ( J:134581 )

• dilated cardiomyopathy develops in mice over 1 year of age

decreased heart left ventricle muscle contractility ( J:134581 )

• left ventricular fractional shortening is reduced in 1 year old mice

growth/size/body

increased heart weight ( J:134581 )

• heart weight to body weight ratio is increased in 1 year old mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
dilated cardiomyopathy		DOID:12930	OMIM:PS115200	J:134581