Analysis Tools|
Allele Symbol Allele Name Allele ID |
Mirc6tm1.1Mzhu targeted mutation 1.1, Min-Sheng Zhu MGI:5907298 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• increase in type IIB fibers in the gastrocnemius muscle of mice with maternally inherited mutant allele
• type IIB fibers in the gastrocnemius muscle of mice with maternally inherited mutant allele are enriched in large fibers unlike wild-type mice
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• fast-twitch muscle hypertrophy is seen in the gastrocnemius, tibialis anterior, and gluteus maximus muscles at P10 but not in mice over 3 weeks of age with a maternally inherited mutant allele
• however, the soleus muscle (slow-twitch muscle) is slightly smaller in neonatal mice with a maternally inherited mutant allele
• muscle mass is similar to wild-type controls in mice with a paternally inherited mutant allele
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• the paternal allele is functionally inactivated
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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