About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tnfrsf14tm1.1Kro
targeted mutation 1.1, Mitchell Kronenberg
MGI:5907516
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Commd10Tg(Vav1-icre)A2Kio/?
Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
involves: C57BL/6NCrl * C57BL/10 * CBA * SJL MGI:5908557


Genotype
MGI:5908557
cn1
Allelic
Composition
Commd10Tg(Vav1-icre)A2Kio/?
Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic
Background
involves: C57BL/6NCrl * C57BL/10 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10Tg(Vav1-icre)A2Kio mutation (3 available); any Commd10 mutation (24 available)
Tnfrsf14tm1.1Kro mutation (1 available); any Tnfrsf14 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• following corneal inoculation of HSV1, corneas have lower viral titers as compared to controls
• myeloid cell infiltration into the cornea 14 days post HSV1 infection is reduced as compared to controls

behavior/neurological
• following corneal inoculation of HSV1, corneal reflexes (as measured by corneal touch threshold) are largely retained in contrast to infected controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory