Analysis Tools
vision/eye
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• following infection with adeno-associated viruses that express a single-guide RNA targeting Amigo1 and a fluorescent reporter (AAV2/1-U6-sgAmigo1-CAG-tdTomato), the size of axons of infected horizontal cells is reduced and some branches stray into the outer nuclear layers
• however, the number of dendritic and axonal synapses and the size of horizontal cell dendrites is normal
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nervous system
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• following infection with adeno-associated viruses that express a single-guide RNA targeting Amigo1 and a fluorescent reporter (AAV2/1-U6-sgAmigo1-CAG-tdTomato), the size of axons of infected horizontal cells is reduced and some branches stray into the outer nuclear layers
• however, the number of dendritic and axonal synapses and the size of horizontal cell dendrites is normal
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