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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tnfrsf14tm1Kro
targeted mutation 1, Mitchell Kronenberg
MGI:5908456
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tnfrsf14tm1Kro/Tnfrsf14tm1Kro C57BL/6-Tnfrsf14tm1Kro MGI:5908554


Genotype
MGI:5908554
hm1
Allelic
Composition		 Tnfrsf14tm1Kro/Tnfrsf14tm1Kro
Genetic
Background		 C57BL/6-Tnfrsf14tm1Kro
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfrsf14tm1Kro mutation (0 available); any Tnfrsf14 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Herpesvirales infection ( J:243038 )
• following corneal inoculation of HSV1, corneas do not become as heavily infiltrated with CD45+ leukocytes as do controls

behavior/neurological
abnormal blinking ( J:243038 )
• following corneal inoculation of HSV1, corneal reflexes (as measured by corneal touch threshold) are largely retained in contrast to infected controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory