All Phenotypes Pcbp1<em2Salr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pcbp1^em2Salr
endonuclease-mediated mutation 2, Stephen A Liebhaber
MGI:5908909

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pcbp1^em2Salr/Pcbp1^em2Salr	C57BL/6-Pcbp1^em2Salr	MGI:5909007
ht2	Pcbp1^em2Salr/Pcbp1⁺	C57BL/6-Pcbp1^em2Salr	MGI:5909006
cx3	Pcbp1^em2Salr/Pcbp1⁺ Pcbp2^tm1.2Salr/Pcbp2⁺	involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * FVB/N	MGI:5909014

Allelic Composition	Pcbp1^em2Salr/Pcbp1^em2Salr
Genetic Background	C57BL/6-Pcbp1^em2Salr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcbp1^em2Salr mutation (0 available); any Pcbp1 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:235912 )

• mice die between E3.5 and E8.5

Allelic Composition	Pcbp1^em2Salr/Pcbp1⁺
Genetic Background	C57BL/6-Pcbp1^em2Salr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcbp1^em2Salr mutation (0 available); any Pcbp1 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body weight ( J:235912 )

• prior to weaning and through adulthood in female and male mice

hematopoietic system

hematopoietic system phenotype ( J:235912 )

N	• mice exhibit normal complete blood counts

Allelic Composition	Pcbp1^em2Salr/Pcbp1⁺ Pcbp2^tm1.2Salr/Pcbp2⁺
Genetic Background	involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcbp1^em2Salr mutation (0 available); any Pcbp1 mutation (33 available)
Pcbp2^tm1.2Salr mutation (0 available); any Pcbp2 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:235912 )

• only 1 mouse survived beyond the first week of life

prenatal lethality, incomplete penetrance ( J:235912 )

• fewer than expected mice are born alive

growth/size/body

decreased body weight ( J:235912 )

• in surviving mice

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