Phenotypes associated with this allele

• Allele Symbol: Ythdc2^em2Embrp
• Allele Name: endonuclease-mediated mutation 2, Ramesh Pillai
• Allele ID: MGI:5911568
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ythdc2^em2Embrp/Ythdc2^em2Embrp	involves: C57BL/6J	MGI:5911997

Genotype
MGI:5911997

hm1

• Allelic Composition: Ythdc2^em2Embrp/Ythdc2^em2Embrp
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

decreased oocyte number ( J:243742 )

♀

azoospermia ( J:243742 )

♂ • in the seminiferous tubules

abnormal female meiosis ( J:243742 )

♀

arrest of male meiosis ( J:243742 )

♂ • due to premature exit from prophase to metaphase

increased male germ cell apoptosis ( J:243742 )

♂

abnormal ovarian follicle morphology ( J:243742 )

♀ • small follicles in some mice

absent ovarian follicles ( J:243742 )

♀ • in some mice

ovary atrophy ( J:243742 )

♀

testicular atrophy ( J:243742 )

♂

female infertility ( J:243742 )

♀

male infertility ( J:243742 )

♂

cellular

decreased oocyte number ( J:243742 )

♀

azoospermia ( J:243742 )

♂ • in the seminiferous tubules

abnormal female meiosis ( J:243742 )

♀

arrest of male meiosis ( J:243742 )

♂ • due to premature exit from prophase to metaphase

increased male germ cell apoptosis ( J:243742 )

♂

endocrine/exocrine glands

abnormal ovarian follicle morphology ( J:243742 )

♀ • small follicles in some mice

absent ovarian follicles ( J:243742 )

♀ • in some mice

ovary atrophy ( J:243742 )

♀

testicular atrophy ( J:243742 )

♂