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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ythdf2tm1.1Doca
targeted mutation 1.1, Donal OCarroll
MGI:5911733
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ythdf2tm1.1Doca/Ythdf2tm1.1Doca Not Specified MGI:5911742
cn2
 		Ythdf2tm1.1Doca/Ythdf2tm1.1Doca
Tg(Zp3-cre)3Mrt/0 		involves: FVB/N MGI:5911743


Genotype
MGI:5911742
hm1
Allelic
Composition		 Ythdf2tm1.1Doca/Ythdf2tm1.1Doca
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf2tm1.1Doca mutation (0 available); any Ythdf2 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:243747 )
• mice are viable and fertile




Genotype
MGI:5911743
cn2
Allelic
Composition		 Ythdf2tm1.1Doca/Ythdf2tm1.1Doca
Tg(Zp3-cre)3Mrt/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Zp3-cre)3Mrt mutation (2 available)
Ythdf2tm1.1Doca mutation (0 available); any Ythdf2 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
maternal effect ( J:243747 )
• fertilized zygotes fail to develop beyond the two-cell stage

reproductive system
female infertility ( J:243747 )
• despite the presence of corpora lutea, normal induced ovulation and normal fertilization




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory