All Phenotypes Ythdf2<tm1.2Doca> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ythdf2^tm1.2Doca
targeted mutation 1.2, Donal OCarroll
MGI:5911734

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ythdf2^tm1.2Doca/Ythdf2^tm1.2Doca	B6.Cg-Ythdf2^tm1.2Doca	MGI:5911746
hm2	Ythdf2^tm1.2Doca/Ythdf2^tm1.2Doca	involves: FVB/N	MGI:5911744

Allelic Composition	Ythdf2^tm1.2Doca/Ythdf2^tm1.2Doca
Genetic Background	B6.Cg-Ythdf2^tm1.2Doca

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf2^tm1.2Doca mutation (0 available); any Ythdf2 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:243747 )

• Background Sensitivity: mice congenic on a C57BL/6 background exhibit increased preweaning lethality compared with mice on a mixed background

Allelic Composition	Ythdf2^tm1.2Doca/Ythdf2^tm1.2Doca
Genetic Background	involves: FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf2^tm1.2Doca mutation (0 available); any Ythdf2 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:243747 )

• half of expected mice are observed at weaning

reproductive system

reproductive system phenotype ( J:243747 )

N	• male mice are fertile and exhibit normal seminiferous tubule histology

female infertility ( J:243747 )

• despite the presence of corpora lutea

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24