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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
dft
deformed tail
MGI:5912231
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
dft/dft B6;FVB-dft/GrsrJ MGI:5912262


Genotype
MGI:5912262
hm1
Allelic
Composition
dft/dft
Genetic
Background
B6;FVB-dft/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
dft mutation (1 available); any dft mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• variability in tail length, with the most severely impacted homozygote having only a short stub of a tail

reproductive system
• intercrosses of homozygotes with heterozygotes yielded an average litter size of only 4 and intercrosses of heterozygotes yielded an average litter size of approximately 5

mortality/aging
• intercrossing heterozygotes with homozygotes yielded only 22.7% mutants instead of the expected 50% and intercrossing heterozygotes yielded only 13.3% mutants instead of the expected 25%, which combined with the lower than normal litter size indicates some loss of homozygotes to prenatal lethality





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory