cardiovascular system
N |
• no increase in heart weight, no dilation, and no fibrosis when tamoxifen is used to induce loss of expression in neonatal mice unlike when expression is absent in embryonic stages
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• in cultured cardiomyocytes after tamoxifen induction 22% become binucleated while very few cells were binucleate before tamoxifen exposure
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• increase in the proportion of cardiomyocytes with unresolved cytokinetic midbody structures indicating failed abscission
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cellular
• increase in the proportion of cardiomyocytes with unresolved cytokinetic midbody structures indicating failed abscission
|
• increase in the proportion of cardiomyocytes with unresolved cytokinetic midbody structures indicating failed abscission
|
muscle
• increase in the proportion of cardiomyocytes with unresolved cytokinetic midbody structures indicating failed abscission
|