Phenotypes associated with this allele

• Allele Symbol: Pias3^tm1.2Asw
• Allele Name: targeted mutation 1.2, Anand Swaroop
• Allele ID: MGI:5927688
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Pias3^tm1.2Asw/Pias3^tm1.2Asw Tg(rx3-icre)1Mjam/0	involves: C57BL/6J * SJL	MGI:5927698

Genotype
MGI:5927698

cx1

• Allelic Composition: Pias3^tm1.2Asw/Pias3^tm1.2Asw; Tg(rx3-icre)1Mjam/0
• Genetic Background: involves: C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal cone electrophysiology ( J:243503 )

• M-cone response to green light flashes in light-adapted P21 mice as measured with ERG was significantly reduced and remained reduced till at least 12 months old

• S-cone response to UV light flashes in light-adapted mice as measured with ERG started reducing from 7 months old

abnormal rod electrophysiology ( J:243503 )

• response to a- and b-waves in dark-adapted mice as measured with ERG started reducing from 7 months old