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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Spata2em1Jliu
endonuclease-mediated mutation 1, Jiali Liu
MGI:6093706
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Spata2em1Jliu/Spata2em1Jliu involves: ICR MGI:6093712


Genotype
MGI:6093712
hm1
Allelic
Composition
Spata2em1Jliu/Spata2em1Jliu
Genetic
Background
involves: ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spata2em1Jliu mutation (0 available); any Spata2 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• reduced differentiating spermatogonia and spermatocytes
• however, Sertoli cell numbers are normal
• at 120 days post parturition
• especially curvilinear velocity
• however, sperm exhibit normal motion morphology, including the lateral amplitude (ALH) or beat cross frequency (BCF)
• thinner and reduced diameter at 120, but not 45, days post parturition
• at 120, but not 45, days post parturition
• at 120, but not 45, days post parturition
• following male mice mated with wild-type female mice
• when sperm is used to fertilize super-ovulated female mice

cellular
• reduced differentiating spermatogonia and spermatocytes
• however, Sertoli cell numbers are normal
• at 120 days post parturition
• especially curvilinear velocity
• however, sperm exhibit normal motion morphology, including the lateral amplitude (ALH) or beat cross frequency (BCF)

endocrine/exocrine glands
• thinner and reduced diameter at 120, but not 45, days post parturition
• at 120, but not 45, days post parturition
• at 120, but not 45, days post parturition





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory