Phenotypes associated with this allele

• Allele Symbol: Rplp1^tm1.1Melt
• Allele Name: targeted mutation 1.1, Matilde E Lleonart
• Allele ID: MGI:6094829
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Rplp1^tm1.1Melt/Rplp1^tm1.2Melt	Not Specified	MGI:6095163

Genotype
MGI:6095163

ht1

• Allelic Composition: Rplp1^tm1.1Melt/Rplp1^tm1.2Melt
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:218949 )

reproductive system

male infertility ( J:218949 )

♂ • despite no histological differences in the testes

digestive/alimentary system

abnormal intestine morphology ( J:218949 )

• perforations in the small and large intestine with yellow-colored meconium ileus

hematopoietic system

small thymus ( J:218949 )

• with abnormal organization

impaired hematopoiesis ( J:218949 )

• in the liver

decreased erythroblast number ( J:218949 )

• in the liver

limbs/digits/tail

abnormal tail morphology ( J:218949 )

• disorganized serial cartilage with enlarged long bones

short tail ( J:218949 )

abnormal tail position or orientation ( J:218949 )

• rigid

kinked tail ( J:218949 )

integument

abnormal skin coloration ( J:218949 )

• yellow abdominal coloration

liver/biliary system

abnormal liver morphology ( J:218949 )

• abnormalities with very little hematopoiesis and erythroblasts and granular cells

growth/size/body

decreased birth body size ( J:218949 )

adipose tissue

abnormal adipose tissue development ( J:218949 )

• poorly differentiated adipoblasts

endocrine/exocrine glands

small thymus ( J:218949 )

• with abnormal organization

immune system

small thymus ( J:218949 )

• with abnormal organization