Phenotypes associated with this allele

• Allele Symbol: Fndc4^tm1.1Mabo
• Allele Name: targeted mutation 1.1, Madeleen Bosma
• Allele ID: MGI:6103906
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fndc4^tm1.1Mabo/Fndc4^tm1.1Mabo	involves: C57BL/6 * BALB/c	MGI:6103907

Genotype
MGI:6103907

hm1

• Allelic Composition: Fndc4^tm1.1Mabo/Fndc4^tm1.1Mabo
• Genetic Background: involves: C57BL/6 * BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

decreased colon length ( J:236896 )

• after DSS (dextran sodium sulfate)-induced colitis

increased susceptibility to induced colitis ( J:236896 )

• after induction with DSS (dextran sodium sulfate)

• increased disease severity

• increased histopathology scores

• increased proinflammatory gene expression

growth/size/body

weight loss ( J:236896 )

• increased weight loss after DSS (dextran sodium sulfate)-induced colitis

immune system

increased susceptibility to induced colitis ( J:236896 )

• after induction with DSS (dextran sodium sulfate)

• increased disease severity

• increased histopathology scores

• increased proinflammatory gene expression