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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Shprhtm1Jhjh
targeted mutation 1, Jan H J Hoeijmakers
MGI:6108184
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Hltftm1.1Hdin/Hltftm1.1Hdin
Shprhtm1Jhjh/Shprhtm1Jhjh 		involves: 129 * C57BL/6 * SJL MGI:6108259


Genotype
MGI:6108259
cx1
Allelic
Composition		 Hltftm1.1Hdin/Hltftm1.1Hdin
Shprhtm1Jhjh/Shprhtm1Jhjh
Genetic
Background		 involves: 129 * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hltftm1.1Hdin mutation (0 available); any Hltf mutation (47 available)
Shprhtm1Jhjh mutation (0 available); any Shprh mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:177630 )
N
• class switch recombination in primary-activated B cells
• normal somatic hypermutation frequency and spectrum in JH4 intronic region in germinal center B cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory