All Phenotypes Zpld1<em1(IMPC)J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Zpld1^em1(IMPC)J
endonuclease-mediated mutation 1, Jackson
MGI:6108892

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zpld1^em1(IMPC)J/Zpld1^em1(IMPC)J	C57BL/6NJ-Zpld1^em1(IMPC)J/Mmjax	MGI:6358227
hm2	Zpld1^em1(IMPC)J/Zpld1^em1(IMPC)J	C57BL/6NJ-Zpld1^em1(IMPC)J/Mmjax	MGI:6370459
ht3	Zpld1^em1(IMPC)J/Zpld1^sprl	(C57BL/6NJ-Zpld1^em1(IMPC)J/Mmjax x B6(129S4)-Zpld1^sprl/Kjn)F1	MGI:6358226

Allelic Composition	Zpld1^em1(IMPC)J/Zpld1^em1(IMPC)J
Genetic Background	C57BL/6NJ-Zpld1^em1(IMPC)J/Mmjax

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zpld1^em1(IMPC)J mutation (2 available); any Zpld1 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:278455 )

N	• homozygotes have normal hearing by ABR and do not display circling behavior

Allelic Composition	Zpld1^em1(IMPC)J/Zpld1^em1(IMPC)J
Genetic Background	C57BL/6NJ-Zpld1^em1(IMPC)J/Mmjax

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zpld1^em1(IMPC)J mutation (2 available); any Zpld1 mutation (25 available)

Data Sources

IMPC Data for Zpld1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - JAX

decreased thigmotaxis ( J:211773 )

IMPC - JAX

hyperactivity ( J:211773 )

IMPC - JAX

Allelic Composition	Zpld1^em1(IMPC)J/Zpld1^sprl
Genetic Background	(C57BL/6NJ-Zpld1^em1(IMPC)J/Mmjax x B6(129S4)-Zpld1^sprl/Kjn)F1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zpld1^em1(IMPC)J mutation (2 available); any Zpld1 mutation (25 available)
Zpld1^sprl mutation (1 available); any Zpld1 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

circling ( J:278455 )

• null homozygotes do not display circling and approximately half of sprl homozygotes do display circling, 27% of compound heterozygotes display circling

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