Phenotypes associated with this allele

• Allele Symbol: Foxi2^tm1.1Akg
• Allele Name: targeted mutation 1.1, Andrew K Groves
• Allele ID: MGI:6113414
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Foxi2^tm1.1Akg/Foxi2^tm1.1Akg	involves: BALB/cJ	MGI:6114102
cx2	Foxi2^tm1.1Akg/Foxi2^tm1.1Akg Foxi3^tm1.2Akg/Foxi3^tm1.2Akg	involves: 129X1/SvJ * BALB/cJ	MGI:6114103

Genotype
MGI:6114102

hm1

• Allelic Composition: Foxi2^tm1.1Akg/Foxi2^tm1.1Akg
• Genetic Background: involves: BALB/cJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:228880 )

• viable and fertile with no gross abnormalities

Genotype
MGI:6114103

cx2

• Allelic Composition: Foxi2^tm1.1Akg/Foxi2^tm1.1Akg; Foxi3^tm1.2Akg/Foxi3^tm1.2Akg
• Genetic Background: involves: 129X1/SvJ * BALB/cJ

nervous system

abnormal nervous system development ( J:228880 )

• no significant difference from mice homozygous null for Foxi3 alone

abnormal vestibulocochlear ganglion morphology ( J:228880 )

• absent or severely deformed

abnormal geniculate ganglion morphology ( J:228880 )

• absent or severely deformed

abnormal trigeminal ganglion morphology ( J:228880 )

• absence of the mandibular branch of the trigeminal ganglion

• however, the ophthalmic and maxillary branches remain