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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stat1m3Btlr
mutation 3, Bruce Beutler
MGI:6113472
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Stat1m3Btlr/Stat1m3Btlr C57BL/6J-Stat1m3Btlr MGI:6113474


Genotype
MGI:6113474
hm1
Allelic
Composition		 Stat1m3Btlr/Stat1m3Btlr
Genetic
Background		 C57BL/6J-Stat1m3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1m3Btlr mutation (0 available); any Stat1 mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
impaired natural killer cell mediated cytotoxicity ( J:254835 )
• reduced ability to kill beta-2-microglobulin deficient cells (NK cell targets)

hematopoietic system
impaired natural killer cell mediated cytotoxicity ( J:254835 )
• reduced ability to kill beta-2-microglobulin deficient cells (NK cell targets)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory