All Phenotypes Cd79a<m2Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cd79a^m2Btlr
mutation 2, Bruce Beutler
MGI:6113480

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd79a^m2Btlr/Cd79a^m2Btlr	C57BL/6J-Cd79a^m2Btlr	MGI:6113482

Allelic Composition	Cd79a^m2Btlr/Cd79a^m2Btlr
Genetic Background	C57BL/6J-Cd79a^m2Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79a^m2Btlr mutation (0 available); any Cd79a mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased B-1 B cell number ( J:254836 )

• in the peripheral blood

decreased IgM level ( J:254836 )

• reduced T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

impaired humoral immune response ( J:254836 )

• reduced T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

hematopoietic system

decreased B-1 B cell number ( J:254836 )

• in the peripheral blood

decreased IgM level ( J:254836 )

• reduced T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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