About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Card11M4Btlr
mutationn 4, Bruce Beutler
MGI:6113504
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Card11M4Btlr/Card11M4Btlr C57BL/6J-Card11M4Btlr MGI:6113506
ht2
 		Card11M4Btlr/Card11+ C57BL/6J-Card11M4Btlr MGI:6113507


Genotype
MGI:6113506
hm1
Allelic
Composition		 Card11M4Btlr/Card11M4Btlr
Genetic
Background		 C57BL/6J-Card11M4Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Card11M4Btlr mutation (0 available); any Card11 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgM level ( J:254856 )
• decreased T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)
impaired humoral immune response ( J:254856 )
• decreased T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

hematopoietic system
decreased IgM level ( J:254856 )
• decreased T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)




Genotype
MGI:6113507
ht2
Allelic
Composition		 Card11M4Btlr/Card11+
Genetic
Background		 C57BL/6J-Card11M4Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Card11M4Btlr mutation (0 available); any Card11 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

immune system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory