Phenotypes associated with this allele

• Allele Symbol: Ppp3cb^M3Btlr
• Allele Name: mutation 3, Bruce Beutler
• Allele ID: MGI:6113566
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ppp3cb^M3Btlr/Ppp3cb^M3Btlr	C57BL/6J-Ppp3cb^M3Btlr	MGI:6113568
ht2	Ppp3cb^M3Btlr/Ppp3cb^+	C57BL/6J-Ppp3cb^M3Btlr	MGI:6113569

Genotype
MGI:6113568

hm1

• Allelic Composition: Ppp3cb^M3Btlr/Ppp3cb^M3Btlr
• Genetic Background: C57BL/6J-Ppp3cb^M3Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased central memory CD4-positive, alpha-beta T cell number ( J:254889 )

• in the peripheral blood

increased central memory CD8 positive, alpha-beta T cell number ( J:254889 )

• in the peripheral blood

decreased CD8-positive, alpha-beta memory T cell number ( J:254889 )

• in the peripheral blood

decreased CD8-positive, naive alpha-beta T cell number ( J:254889 )

• in the peripheral blood

hematopoietic system

increased central memory CD4-positive, alpha-beta T cell number ( J:254889 )

• in the peripheral blood

increased central memory CD8 positive, alpha-beta T cell number ( J:254889 )

• in the peripheral blood

decreased CD8-positive, alpha-beta memory T cell number ( J:254889 )

• in the peripheral blood

decreased CD8-positive, naive alpha-beta T cell number ( J:254889 )

• in the peripheral blood

Genotype
MGI:6113569

ht2

• Allelic Composition: Ppp3cb^M3Btlr/Ppp3cb⁺
• Genetic Background: C57BL/6J-Ppp3cb^M3Btlr

immune system

increased central memory CD4-positive, alpha-beta T cell number ( J:254889 )

• in the peripheral blood

decreased CD8-positive, alpha-beta memory T cell number ( J:254889 )

• in the peripheral blood

hematopoietic system

increased central memory CD4-positive, alpha-beta T cell number ( J:254889 )

• in the peripheral blood

decreased CD8-positive, alpha-beta memory T cell number ( J:254889 )

• in the peripheral blood