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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ticam2M3Btlr
mutation 3, Bruce Beutler
MGI:6113633
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ticam2M3Btlr/Ticam2M3Btlr C57BL/6J-Ticam2M3Btlr MGI:6113635
ht2
 		Ticam2M3Btlr/Ticam2+ C57BL/6J-Ticam2M3Btlr MGI:6113636


Genotype
MGI:6113635
hm1
Allelic
Composition		 Ticam2M3Btlr/Ticam2M3Btlr
Genetic
Background		 C57BL/6J-Ticam2M3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ticam2M3Btlr mutation (0 available); any Ticam2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:254912 )
• decreased TNFalpha secretion in response to the Toll-like receptor 4 (TLR4) ligand, LPS




Genotype
MGI:6113636
ht2
Allelic
Composition		 Ticam2M3Btlr/Ticam2+
Genetic
Background		 C57BL/6J-Ticam2M3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ticam2M3Btlr mutation (0 available); any Ticam2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:254912 )
• decreased TNFalpha secretion in response to the Toll-like receptor 4 (TLR4) ligand, LPS




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory