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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Blkm1Btlr
mutation 1, Bruce Beutler
MGI:6113863
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Blkm1Btlr/Blkm1Btlr C57BL/6J-Blkm1Btlr MGI:6113865


Genotype
MGI:6113865
hm1
Allelic
Composition		 Blkm1Btlr/Blkm1Btlr
Genetic
Background		 C57BL/6J-Blkm1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Blkm1Btlr mutation (0 available); any Blk mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased interleukin-1 beta secretion ( J:255004 )
• in response to LPS-primed macrophages simulated with nigericin and flagellin

hematopoietic system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory