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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd8b1M1Btlr
mutation 1, Bruce Beutler
MGI:6113877
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd8b1M1Btlr/Cd8b1M1Btlr C57BL/6J-Cd8b1M1Btlr MGI:6113879
ht2
 		Cd8b1M1Btlr/Cd8b1+ C57BL/6J-Cd8b1M1Btlr MGI:6113880


Genotype
MGI:6113879
hm1
Allelic
Composition		 Cd8b1M1Btlr/Cd8b1M1Btlr
Genetic
Background		 C57BL/6J-Cd8b1M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd8b1M1Btlr mutation (0 available); any Cd8b1 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased IgG level ( J:255009 )
• increased T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)
enhanced humoral immune response ( J:255009 )
• increased T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

hematopoietic system
increased IgG level ( J:255009 )
• increased T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)




Genotype
MGI:6113880
ht2
Allelic
Composition		 Cd8b1M1Btlr/Cd8b1+
Genetic
Background		 C57BL/6J-Cd8b1M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd8b1M1Btlr mutation (0 available); any Cd8b1 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system

hematopoietic system




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory