About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ighdm2Btlr
mutation 2, Bruce Beutler
MGI:6114054
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ighdm2Btlr/Ighdm2Btlr C57BL/6J-Ighdm2Btlr MGI:6114056
ht2
 		Ighdm2Btlr/Ighd+ C57BL/6J-Ighdm2Btlr MGI:6114057


Genotype
MGI:6114056
hm1
Allelic
Composition		 Ighdm2Btlr/Ighdm2Btlr
Genetic
Background		 C57BL/6J-Ighdm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighdm2Btlr mutation (0 available); any Ighd mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood
decreased IgD level ( J:255203 )
• reduced expression of IgD on peripheral blood B cells

immune system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood
decreased IgD level ( J:255203 )
• reduced expression of IgD on peripheral blood B cells




Genotype
MGI:6114057
ht2
Allelic
Composition		 Ighdm2Btlr/Ighd+
Genetic
Background		 C57BL/6J-Ighdm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighdm2Btlr mutation (0 available); any Ighd mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood

hematopoietic system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory