About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pik3ap1m2Btlr
mutation 2, Bruce Beutler
MGI:6114668
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pik3ap1m2Btlr/Pik3ap1m2Btlr C57BL/6J-Pik3ap1m2Btlr MGI:6114670


Genotype
MGI:6114670
hm1
Allelic
Composition		 Pik3ap1m2Btlr/Pik3ap1m2Btlr
Genetic
Background		 C57BL/6J-Pik3ap1m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3ap1m2Btlr mutation (0 available); any Pik3ap1 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B-1a cell number ( J:255271 )
• in the peripheral blood
increased B-1b cell number ( J:255271 )
• in the peripheral blood
increased IgM level ( J:255271 )
• diminished T-independent antibody (IgM) response to NP-Ficoll
impaired humoral immune response ( J:255271 )
• diminished T-independent antibody (IgM) response to NP-Ficoll

hematopoietic system
decreased B-1a cell number ( J:255271 )
• in the peripheral blood
increased B-1b cell number ( J:255271 )
• in the peripheral blood
increased IgM level ( J:255271 )
• diminished T-independent antibody (IgM) response to NP-Ficoll




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory