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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ticam1M3Btlr
mutation 3, Bruce Beutler
MGI:6114756
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ticam1M3Btlr/Ticam1M3Btlr C57BL/6J-Ticam1M3Btlr MGI:6114759
ht2
 		Ticam1M3Btlr/Ticam1+ C57BL/6J-Ticam1M3Btlr MGI:6114760


Genotype
MGI:6114759
hm1
Allelic
Composition		 Ticam1M3Btlr/Ticam1M3Btlr
Genetic
Background		 C57BL/6J-Ticam1M3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ticam1M3Btlr mutation (0 available); any Ticam1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:255300 )
• decreased in tumor necrosis factor (TNF-alpha) production in response to TLR4 ligand, lipopolysaccharide (LPS)




Genotype
MGI:6114760
ht2
Allelic
Composition		 Ticam1M3Btlr/Ticam1+
Genetic
Background		 C57BL/6J-Ticam1M3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ticam1M3Btlr mutation (0 available); any Ticam1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:255300 )
• intermediate decreased in tumor necrosis factor (TNF-alpha) production in response to TLR4 ligand, lipopolysaccharide (LPS)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory