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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ccdc62em1Jxia
endonuclease-mediated mutation 1, Jun Xia
MGI:6116688
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ccdc62em1Jxia/Ccdc62em1Jxia C57BL/6-Ccdc62em1Jxia MGI:6116697
ht2
Ccdc62em1Jxia/Ccdc62+ C57BL/6-Ccdc62em1Jxia MGI:6116698


Genotype
MGI:6116697
hm1
Allelic
Composition
Ccdc62em1Jxia/Ccdc62em1Jxia
Genetic
Background
C57BL/6-Ccdc62em1Jxia
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc62em1Jxia mutation (0 available); any Ccdc62 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• fertile
• litter size
• most sperm malformed
• enclosed within a cytoplasm bag
• wrapped around sperm head
• flagellum midpiece wrapped around head
• enclosed within a cytoplasm bag
• motility of cauda epididymal sperm reduced to less than 10% of wild-type
• after 2 months mating with wild-type or heterozygous KO females
• normal sperm count

cellular
• most sperm malformed
• enclosed within a cytoplasm bag
• wrapped around sperm head
• flagellum midpiece wrapped around head
• enclosed within a cytoplasm bag
• motility of cauda epididymal sperm reduced to less than 10% of wild-type




Genotype
MGI:6116698
ht2
Allelic
Composition
Ccdc62em1Jxia/Ccdc62+
Genetic
Background
C57BL/6-Ccdc62em1Jxia
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc62em1Jxia mutation (0 available); any Ccdc62 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• males are fertile, generating a normal litter size when mated with heterozygous KO females; sperm count is normal





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory