Phenotypes associated with this allele

• Allele Symbol: Iho1^tm1.2Atot
• Allele Name: targeted mutation 1.2, Attila Toth
• Allele ID: MGI:6116835
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Iho1^tm1.2Atot/Iho1^tm1.2Atot	involves: 129S1/Sv * 129X1/SvJ * CD-1	MGI:7450826

Genotype
MGI:7450826

hm1

• Allelic Composition: Iho1^tm1.2Atot/Iho1^tm1.2Atot
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal spermatocyte morphology ( J:276412 )

• only ANKRD31, MEI4, and REC114 foci, but not aggregates, are diminished in spermatocytes

• ANKRD31 aggregates form efficiently in zygotene spermatocytes; these aggregates always colocalize with aggregates of MEI4 and REC114

• ANKRD31 aggregates also colocalize with PAR (pseudoautosomal region) FISH signals in late zygotene-like spermatocytes

cellular

abnormal spermatocyte morphology ( J:276412 )

• only ANKRD31, MEI4, and REC114 foci, but not aggregates, are diminished in spermatocytes

• ANKRD31 aggregates form efficiently in zygotene spermatocytes; these aggregates always colocalize with aggregates of MEI4 and REC114

• ANKRD31 aggregates also colocalize with PAR (pseudoautosomal region) FISH signals in late zygotene-like spermatocytes