Phenotypes associated with this allele

• Allele Symbol: Cd99l2^tm1.2Dvst
• Allele Name: targeted mutation 1.2, Dietmar Vestweber
• Allele ID: MGI:6117037
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd99l2^tm1.2Dvst/Cd99l2^tm1.2Dvst	involves: 129S6/SvEvTac * BALB/c * C57BL/6	MGI:6117086

Genotype
MGI:6117086

hm1

• Allelic Composition: Cd99l2^tm1.2Dvst/Cd99l2^tm1.2Dvst
• Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:193021 )

N • litter size, breeding efficiency and Mendelian ratios

immune system

abnormal cellular extravasation ( J:193021 )

• 23.8% reduction in transmigration of wild-type bone marrow-derived neutrophils through knockout mouse-derived lung primary endothelial cells in vitro

• 28.8% reduction in transmigration of OVA antigen-stimulated T cells from OT-II (Tg(TcraTcrb)425Cbn) mice through knockout mouse-derived lung primary endothelial cells in vitro

cellular

cellular phenotype ( J:193021 )

N • knockout mouse bone marrow-derived leukocyte rolling and tethering within wild-type mouse cremaster venules, 4 h after intrascrotal injection with Il1b

N • delayed-type hypersensitivity (DTH) reaction after injection of DNFB-treated knockout mouse bone marrow-derived T cells into DNFB-treated wild-type ears

abnormal cellular extravasation ( J:193021 )

• 23.8% reduction in transmigration of wild-type bone marrow-derived neutrophils through knockout mouse-derived lung primary endothelial cells in vitro

• 28.8% reduction in transmigration of OVA antigen-stimulated T cells from OT-II (Tg(TcraTcrb)425Cbn) mice through knockout mouse-derived lung primary endothelial cells in vitro

hematopoietic system

hematopoietic system phenotype ( J:193021 )

N • peripheral leukocyte count

abnormal cellular extravasation ( J:193021 )

• 23.8% reduction in transmigration of wild-type bone marrow-derived neutrophils through knockout mouse-derived lung primary endothelial cells in vitro

• 28.8% reduction in transmigration of OVA antigen-stimulated T cells from OT-II (Tg(TcraTcrb)425Cbn) mice through knockout mouse-derived lung primary endothelial cells in vitro

embryo

embryo phenotype ( J:193021 )

N • embryonic development