Analysis Tools
hematopoietic system
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• 90% loss of TCRVgamma7+ intraepithelial lymphocytes (IELs) in the gut with or without doxycycline administration from age 11 weeks
• almost total loss of TCRVgamma7GL2+ IELs in the gut with or without doxycycline administration from age 11 weeks
• normal CD122hi Lag3hi Thy1- TCRVgamma7+ IELs (most also Ki67+) in the gut after doxycycline administration from age 11 weeks
• normal TCRVgamma7+ and TCRVgamma7GL2+ IEL cell numbers in the gut after doxycycline administration from age 5 or 21 days
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immune system
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• 90% loss of TCRVgamma7+ intraepithelial lymphocytes (IELs) in the gut with or without doxycycline administration from age 11 weeks
• almost total loss of TCRVgamma7GL2+ IELs in the gut with or without doxycycline administration from age 11 weeks
• normal CD122hi Lag3hi Thy1- TCRVgamma7+ IELs (most also Ki67+) in the gut after doxycycline administration from age 11 weeks
• normal TCRVgamma7+ and TCRVgamma7GL2+ IEL cell numbers in the gut after doxycycline administration from age 5 or 21 days
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