All Phenotypes H2-D1<b-em2Dvs> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

H2-D1^b-em2Dvs
endonuclease-mediated mutation 2, David V Serreze
MGI:6118958

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	H2-D1^b-em2Dvs/H2-D1^b-em2Dvs	NOD/ShiLtDvs-H2-D1^b-em2Dvs/Dvs	MGI:6118960

Allelic Composition	H2-D1^b-em2Dvs/H2-D1^b-em2Dvs
Genetic Background	NOD/ShiLtDvs-H2-D1^b-em2Dvs/Dvs

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2-D1^b-em2Dvs mutation (0 available); any H2-D1 mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal immune system physiology ( J:257229 )

• insulitis is decreased at 10-15 weeks of age and diabetes onset is delayed and less severe, but not ablated, relative to wild-type controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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