Phenotypes associated with this allele

• Allele Symbol: Zmynd11^{em1(IMPC)Wtsi}
• Allele Name: endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• Allele ID: MGI:6119402
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zmynd11^em1(IMPC)Wtsi/Zmynd11^em1(IMPC)Wtsi	C57BL/6N-Zmynd11^em1(IMPC)Wtsi/WtsiIeg	MGI:6161269
ht2	Zmynd11^em1(IMPC)Wtsi/Zmynd11^+	C57BL/6N-Zmynd11^em1(IMPC)Wtsi/WtsiIeg	MGI:6263935

Genotype
MGI:6161269

hm1

• Allelic Composition: Zmynd11^{em1(IMPC)Wtsi}/Zmynd11^{em1(IMPC)Wtsi}
• Genetic Background: C57BL/6N-Zmynd11^{em1(IMPC)Wtsi}/WtsiIeg

Data Sources

IMPC Data for Zmynd11

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vertebral artery morphology ( J:239583 )

DMDD

abnormal vertebral artery topology ( J:239583 )

DMDD

dilated liver sinusoidal space ( J:239583 )

DMDD

umbilical vein stenosis ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal ductus venosus valve topology ( J:239583 )

DMDD

abnormal hepatic vein morphology ( J:239583 )

DMDD

abnormal inferior vena cava morphology ( J:239583 )

DMDD

thin myocardium ( J:239583 )

DMDD

abnormal coronary sinus connection ( J:239583 )

DMDD

abnormal heart atrium morphology ( J:239583 )

DMDD

perimembraneous ventricular septal defect ( J:239583 )

DMDD

craniofacial

cleft palate ( J:239583 )

DMDD

digestive/alimentary system

cleft palate ( J:239583 )

DMDD

embryo

umbilical vein stenosis ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal Mullerian duct topology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal cystic duct morphology ( J:239583 )

DMDD

abnormal biliary ductule morphology ( J:239583 )

DMDD

absent thyroid gland isthmus ( J:239583 )

DMDD

small ovary ( J:239583 )

DMDD

abnormal testis morphology ( J:239583 )

DMDD

growth/size/body

cleft palate ( J:239583 )

DMDD

heterochrony ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

liver/biliary system

dilated liver sinusoidal space ( J:239583 )

DMDD

abnormal cystic duct morphology ( J:239583 )

DMDD

abnormal biliary ductule morphology ( J:239583 )

DMDD

herniated liver ( J:239583 )

DMDD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

muscle

thin myocardium ( J:239583 )

DMDD

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal diaphragm morphology ( J:239583 )

DMDD

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

nervous system

abnormal forebrain morphology ( J:239583 )

DMDD

abnormal hypoglossal nerve topology ( J:239583 )

DMDD

reproductive system

small ovary ( J:239583 )

DMDD

abnormal testis morphology ( J:239583 )

DMDD

respiratory system

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

small lung ( J:239583 )

DMDD

skeleton

abnormal rib morphology ( J:239583 )

DMDD

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD

Genotype
MGI:6263935

ht2

• Allelic Composition: Zmynd11^{em1(IMPC)Wtsi}/Zmynd11⁺
• Genetic Background: C57BL/6N-Zmynd11^{em1(IMPC)Wtsi}/WtsiIeg

Data Sources

IMPC Data for Zmynd11

homeostasis/metabolism

increased circulating thyroxine level ( J:211773 )

♀

IMPC - WTSI