Phenotypes associated with this allele

• Allele Symbol: Dsc3^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6120697
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dsc3^tm1b(EUCOMM)Wtsi/Dsc3^tm1b(EUCOMM)Wtsi	C57BL/6N-Dsc3^tm1b(EUCOMM)Wtsi/H	MGI:6262321
ht2	Dsc3^tm1b(EUCOMM)Wtsi/Dsc3^+	C57BL/6N-Dsc3^tm1b(EUCOMM)Wtsi/H	MGI:6262320

Genotype
MGI:6262321

hm1

• Allelic Composition: Dsc3^{tm1b(EUCOMM)Wtsi}/Dsc3^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Dsc3^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0598_4_A12

Data Sources

IMPC Data for Dsc3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6262320

ht2

• Allelic Composition: Dsc3^{tm1b(EUCOMM)Wtsi}/Dsc3⁺
• Genetic Background: C57BL/6N-Dsc3^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0598_4_A12

Data Sources

IMPC Data for Dsc3

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - HAR

decreased thigmotaxis ( J:211773 )

♂

IMPC - HAR

hyperactivity ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

decreased fasting circulating glucose level ( J:211773 )

♂

IMPC - HAR

nervous system

absent optic nerve ( J:211773 )

♀

IMPC - HAR

vision/eye

absent optic nerve ( J:211773 )

♀

IMPC - HAR