Phenotypes associated with this allele

• Allele Symbol: Bscl2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6120702
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bscl2^tm1b(EUCOMM)Hmgu/Bscl2^tm1b(EUCOMM)Hmgu	C57BL/6N-Bscl2^tm1b(EUCOMM)Hmgu/Ics	MGI:6262003

Genotype
MGI:6262003

hm1

• Allelic Composition: Bscl2^{tm1b(EUCOMM)Hmgu}/Bscl2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Bscl2^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0757_2_A10

Data Sources

IMPC Data for Bscl2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♀

IMPC - ICS

behavior/neurological

increased fluid intake ( J:211773 )

♂

IMPC - ICS

increased food intake ( J:211773 )

♂

IMPC - ICS

abnormal gait ( J:211773 )

IMPC - ICS

decreased locomotor activity ( J:211773 )

♂

IMPC - ICS

growth/size/body

increased lean body mass ( J:211773 )

IMPC - ICS

decreased body length ( J:211773 )

♀

IMPC - ICS

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

IMPC - ICS

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - ICS

increased mean corpuscular volume ( J:211773 )

IMPC - ICS

increased neutrophil cell number ( J:211773 )

IMPC - ICS

increased large unstained cell number ( J:211773 )

IMPC - ICS

increased monocyte cell number ( J:211773 )

♀

IMPC - ICS

homeostasis/metabolism

increased circulating glucose level ( J:211773 )

♂

IMPC - ICS

increased fasting circulating glucose level ( J:211773 )

IMPC - ICS

increased circulating cholesterol level ( J:211773 )

IMPC - ICS

increased circulating HDL cholesterol level ( J:211773 )

IMPC - ICS

increased circulating calcium level ( J:211773 )

IMPC - ICS

increased circulating phosphate level ( J:211773 )

IMPC - ICS

increased circulating alanine transaminase level ( J:211773 )

IMPC - ICS

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - ICS

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - ICS

increased circulating serum albumin level ( J:211773 )

IMPC - ICS

increased circulating total protein level ( J:211773 )

IMPC - ICS

decreased respiratory quotient ( J:211773 )

♂

IMPC - ICS

improved glucose tolerance ( J:211773 )

♀

IMPC - ICS

immune system

increased neutrophil cell number ( J:211773 )

IMPC - ICS

increased large unstained cell number ( J:211773 )

IMPC - ICS

increased monocyte cell number ( J:211773 )

♀

IMPC - ICS

limbs/digits/tail

short tibia ( J:211773 )

IMPC - ICS

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - ICS

skeleton

short tibia ( J:211773 )

IMPC - ICS

abnormal bone structure ( J:211773 )

♀

IMPC - ICS

decreased bone mineral content ( J:211773 )

♀

IMPC - ICS

vision/eye

increased cornea thickness ( J:211773 )

♀

IMPC - ICS

decreased total retina thickness ( J:211773 )

IMPC - ICS