Phenotypes associated with this allele

• Allele Symbol: Actr5^{tm2b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6120757
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Actr5^tm2b(EUCOMM)Wtsi/Actr5^tm2b(EUCOMM)Wtsi	C57BL/6N-Actr5^tm2b(EUCOMM)Wtsi/Bay	MGI:6261793
ht2	Actr5^tm2b(EUCOMM)Wtsi/Actr5^+	C57BL/6N-Actr5^tm2b(EUCOMM)Wtsi/Bay	MGI:6288313

Genotype
MGI:6261793

hm1

• Allelic Composition: Actr5^{tm2b(EUCOMM)Wtsi}/Actr5^{tm2b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Actr5^{tm2b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0792_4_E09

Data Sources

IMPC Data for Actr5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo turning ( J:211773 )

IMPC - BCM

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal forebrain development ( J:211773 )

IMPC - BCM

abnormal hindbrain development ( J:211773 )

IMPC - BCM

abnormal midbrain development ( J:211773 )

IMPC - BCM

Genotype
MGI:6288313

ht2

• Allelic Composition: Actr5^{tm2b(EUCOMM)Wtsi}/Actr5⁺
• Genetic Background: C57BL/6N-Actr5^{tm2b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0792_4_E09

Data Sources

IMPC Data for Actr5

behavior/neurological

increased exploration in new environment ( J:211773 )

♀

IMPC - BCM