Phenotypes associated with this allele

• Allele Symbol: Eps8l2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6120769
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eps8l2^tm1b(EUCOMM)Wtsi/Eps8l2^tm1b(EUCOMM)Wtsi	C57BL/6N-Eps8l2^tm1b(EUCOMM)Wtsi/H	MGI:6262380

Genotype
MGI:6262380

hm1

• Allelic Composition: Eps8l2^{tm1b(EUCOMM)Wtsi}/Eps8l2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Eps8l2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0679_3_D06

Data Sources

IMPC Data for Eps8l2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired cued conditioning behavior ( J:211773 )

♀

IMPC - HAR

abnormal startle reflex ( J:211773 )

IMPC - HAR

decreased startle reflex ( J:211773 )

♂

IMPC - HAR

craniofacial

abnormal snout morphology ( J:211773 )

♂

IMPC - HAR

growth/size/body

abnormal snout morphology ( J:211773 )

♂

IMPC - HAR

hearing/vestibular/ear

abnormal ear morphology ( J:211773 )

♂

IMPC - HAR

hematopoietic system

increased basophil cell number ( J:211773 )

♂

IMPC - HAR

decreased erythrocyte cell number ( J:211773 )

IMPC - HAR

increased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

increased monocyte cell number ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

IMPC - HAR

decreased circulating cholesterol level ( J:211773 )

IMPC - HAR

decreased circulating calcium level ( J:211773 )

♀

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - HAR

immune system

increased basophil cell number ( J:211773 )

♂

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

increased monocyte cell number ( J:211773 )

♀

IMPC - HAR

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - HAR