Phenotypes associated with this allele

• Allele Symbol: Taf2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6120788
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Taf2^tm1b(EUCOMM)Hmgu/Taf2^tm1b(EUCOMM)Hmgu	C57BL/6N-Taf2^tm1b(EUCOMM)Hmgu/Ics	MGI:6263631
ht2	Taf2^tm1b(EUCOMM)Hmgu/Taf2^+	C57BL/6N-Taf2^tm1b(EUCOMM)Hmgu/Ics	MGI:6263630

Genotype
MGI:6263631

hm1

• Allelic Composition: Taf2^{tm1b(EUCOMM)Hmgu}/Taf2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Taf2^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0595_7_D08

Data Sources

IMPC Data for Taf2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:6263630

ht2

• Allelic Composition: Taf2^{tm1b(EUCOMM)Hmgu}/Taf2⁺
• Genetic Background: C57BL/6N-Taf2^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0595_7_D08

Data Sources

IMPC Data for Taf2

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - ICS

hyperactivity ( J:211773 )

IMPC - ICS

homeostasis/metabolism

abnormal cholesterol homeostasis ( J:211773 )

IMPC - ICS

increased circulating cholesterol level ( J:211773 )

IMPC - ICS

increased circulating HDL cholesterol level ( J:211773 )

IMPC - ICS

limbs/digits/tail

long tibia ( J:211773 )

♂

IMPC - ICS

skeleton

long tibia ( J:211773 )

♂

IMPC - ICS