Phenotypes associated with this allele

• Allele Symbol: Ampd2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6120811
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ampd2^tm1b(EUCOMM)Hmgu/Ampd2^tm1b(EUCOMM)Hmgu	C57BL/6N-Ampd2^tm1b(EUCOMM)Hmgu/H	MGI:6261856
ht2	Ampd2^tm1b(EUCOMM)Hmgu/Ampd2^+	C57BL/6N-Ampd2^tm1b(EUCOMM)Hmgu/H	MGI:6261855

Genotype
MGI:6261856

hm1

• Allelic Composition: Ampd2^{tm1b(EUCOMM)Hmgu}/Ampd2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Ampd2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0682_1_G04

Data Sources

IMPC Data for Ampd2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

thrombocytosis ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

♂

IMPC - HAR

increased circulating cholesterol level ( J:211773 )

♂

IMPC - HAR

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HAR

increased circulating amylase level ( J:211773 )

♂

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6261855

ht2

• Allelic Composition: Ampd2^{tm1b(EUCOMM)Hmgu}/Ampd2⁺
• Genetic Background: C57BL/6N-Ampd2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0682_1_G04

Data Sources

IMPC Data for Ampd2

hematopoietic system

decreased hematocrit ( J:211773 )

IMPC - HAR

increased mean corpuscular hemoglobin concentration ( J:211773 )

IMPC - HAR

increased red blood cell distribution width ( J:211773 )

♂

IMPC - HAR

increased mean platelet volume ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

increased circulating potassium level ( J:211773 )

♀

IMPC - HAR