Phenotypes associated with this allele

• Allele Symbol: Camk2b^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6120813
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Camk2b^tm1b(EUCOMM)Hmgu/Camk2b^tm1b(EUCOMM)Hmgu	C57BL/6N-Camk2b^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262027
ht2	Camk2b^tm1b(EUCOMM)Hmgu/Camk2b^+	C57BL/6N-Camk2b^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262026

Genotype
MGI:6262027

hm1

• Allelic Composition: Camk2b^{tm1b(EUCOMM)Hmgu}/Camk2b^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Camk2b^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0667_4_A12

Data Sources

IMPC Data for Camk2b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262026

ht2

• Allelic Composition: Camk2b^{tm1b(EUCOMM)Hmgu}/Camk2b⁺
• Genetic Background: C57BL/6N-Camk2b^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0667_4_A12

Data Sources

IMPC Data for Camk2b

behavior/neurological

decreased anxiety-related response ( J:211773 )

♂

IMPC - HMGU

decreased vertical activity ( J:211773 )

IMPC - HMGU

hyperactivity ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

improved glucose tolerance ( J:211773 )

♂

IMPC - HMGU

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - HMGU