Phenotypes associated with this allele

• Allele Symbol: Pepd^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6120820
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pepd^tm1b(KOMP)Wtsi/Pepd^tm1b(KOMP)Wtsi	C57BL/6N-Pepd^tm1b(KOMP)Wtsi/Ieg	MGI:6263141

Genotype
MGI:6263141

hm1

• Allelic Composition: Pepd^{tm1b(KOMP)Wtsi}/Pepd^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Pepd^{tm1b(KOMP)Wtsi}/Ieg
• Cell Lines: EPD0224_1_C04

Data Sources

IMPC Data for Pepd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - HMGU

increased thigmotaxis ( J:211773 )

IMPC - HMGU

decreased grip strength ( J:211773 )

♂

IMPC - HMGU

decreased vertical activity ( J:211773 )

♀

IMPC - HMGU

decreased locomotor activity ( J:211773 )

♀

IMPC - HMGU

hyperactivity ( J:211773 )

♀

IMPC - HMGU

cardiovascular system

decreased heart rate ( J:211773 )

IMPC - HMGU

prolonged RR interval ( J:211773 )

IMPC - HMGU

digestive/alimentary system

small stomach ( J:211773 )

♀

IMPC - HMGU

hematopoietic system

decreased B cell number ( J:211773 )

♂

IMPC - HMGU

decreased B-2 B cell number ( J:211773 )

♂

IMPC - HMGU

decreased follicular B cell number ( J:211773 )

♂

IMPC - HMGU

decreased CD5-positive Ly6C-positive T cell number ( J:211773 )

♂

IMPC - HMGU

homeostasis/metabolism

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HMGU

decreased circulating iron level ( J:211773 )

♂

IMPC - HMGU

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - HMGU

increased circulating unsaturated transferrin level ( J:211773 )

IMPC - HMGU

immune system

decreased B cell number ( J:211773 )

♂

IMPC - HMGU

decreased B-2 B cell number ( J:211773 )

♂

IMPC - HMGU

decreased follicular B cell number ( J:211773 )

♂

IMPC - HMGU

decreased CD5-positive Ly6C-positive T cell number ( J:211773 )

♂

IMPC - HMGU

enlarged lymph nodes ( J:211773 )

♂

IMPC - HMGU

limbs/digits/tail

short tibia ( J:211773 )

IMPC - HMGU

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU

skeleton

short tibia ( J:211773 )

IMPC - HMGU

decreased bone mineral content ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU

abnormal retina morphology ( J:211773 )

IMPC - HMGU