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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dnpepem1Dlp
endonuclease-mediated mutation 1, Eric Delpire
MGI:6120903
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dnpepem1Dlp/Dnpepem1Dlp involves: C57BL/6 * C57BL/6J * DBA/2 MGI:6693728


Genotype
MGI:6693728
hm1
Allelic
Composition		 Dnpepem1Dlp/Dnpepem1Dlp
Genetic
Background		 involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnpepem1Dlp mutation (1 available); any Dnpep mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:256298 )
• homozygous mutant mice are viable and overtly normal; isolated kidney lysates retain cleavage activity of a recombinant GST-STK39 fusion protein, indicating that a protease other than DNPEP also mediates proteolytic cleavage of STK39 (also known as SPAK, STE20/SPS1-related proline/alanine-rich kinase)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory