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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adamts16em2(IMPC)H
endonuclease-mediated mutation 2, Harwell
MGI:6140145
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adamts16em2(IMPC)H/Adamts16em2(IMPC)H C57BL/6NTac-Adamts16em2(IMPC)H MGI:7260117


Genotype
MGI:7260117
hm1
Allelic
Composition		 Adamts16em2(IMPC)H/Adamts16em2(IMPC)H
Genetic
Background		 C57BL/6NTac-Adamts16em2(IMPC)H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts16em2(IMPC)H mutation (2 available); any Adamts16 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:283272 )
N
• unexpectedly, male mice undergo normal primary sex determination and develop testes in the fetal period; adult males have no defects in testicular descent and show normal fertility at 3 and 6 months of age
• female mice are also fertile with no apparent morphological defects in the reproductive system
decreased testis weight ( J:283272 )
• adult males show a small but significant (~10%) decrease in average testis weight relative to age-matched controls
• however, adult testicular histology is normal

endocrine/exocrine glands
decreased testis weight ( J:283272 )
• adult males show a small but significant (~10%) decrease in average testis weight relative to age-matched controls
• however, adult testicular histology is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory