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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kcnj6em1.1Ktaka
endonuclease-mediated mutation 1.1, Kazuo Takahama
MGI:6144032
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Kcnj6em1.1Ktaka/Kcnj6em1.1Ktaka
Slc6a3tm1.1(cre)Bkmn/Slc6a3+
involves: C57BL/6J * C57BL/6N MGI:6144037


Genotype
MGI:6144037
cn1
Allelic
Composition
Kcnj6em1.1Ktaka/Kcnj6em1.1Ktaka
Slc6a3tm1.1(cre)Bkmn/Slc6a3+
Genetic
Background
involves: C57BL/6J * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnj6em1.1Ktaka mutation (0 available); any Kcnj6 mutation (26 available)
Slc6a3tm1.1(cre)Bkmn mutation (3 available); any Slc6a3 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice show decreased immobility time in the forced swimming test
• however, locomotor activity in the open field is normal and mice show normal general behaviors such as gait posture

nervous system
• dopamine and baclofen both fail to cause currents in single putative dopamine neurons from the ventral tegmental area
• however, glutamic acid causes currents to the same extent as that in VTA neurons from controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory